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Overview

About DNA

These days, we have heard people talking about Genetic testing. But, do we know what it is all about? Genetic testing involves examining your DNA and making you aware of any genetic disorder or illness that might occur in the near future. Though genetic testing is really helpful in diagnosing various ailments and helps in the treatment of the same, it too has limitations such as a positive report doesn’t mean that you may get susceptible to any disease and vice versa. The best option is to undergo consultation with your concerned doctor after getting the report.

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Why it's done

Predictive genetic testing is really helpful in analyzing the risk of any genetic abnormality in a person and also guiding them to take timely treatment for the same. There are various types of genetic testing available in the market for different types of concerns. They are as follows:

Diagnostic testing

If you are experiencing any sort of illness with regard to genetic changes, often known as mutated genes, genetic testing will prove helpful in examining that disorder. This helps diagnose Huntington’s disease or cystic fibrosis.

Presymptomatic and predictive testing

This type of testing is done to determine the risk of developing certain types of cancer. Usually, this test is done when you have a history of any genetic disorder.

Pharmacogenetics

For a prevailing health condition or illness, genetic testing will help determine the type of medication and treatment best suited for you.

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Prenatal Testing

Carrier testing

This type of test is highly recommended for would-be parents before planning to have a baby. Reason being, a family history of a genetic disorder such as cystic fibrosis or sickle cell anemia. As the name suggests, this test is just to determine if any of the partners is the carrier of any sort of genetic disease prevailing in their family. If you are searching for a carrier screening test in UAE, you must book an appointment with Uturn9, one of the safest and most reliable diagnostic centers in the UAE.

Prenatal testing

To detect genetic abnormalities in pregnancy, prenatal testing is recommended. This type of testing is done to diagnose down syndrome, trisomy 13, and trisomy 18. It is completely a non-invasive procedure as the test is done by examining free-floating DNA known as cell-free DNA (cfDNA). In this, the mother’s blood is taken for testing thus not harming the fetus at all.

So, if there are any chances of genetic abnormalities in pregnancy, one must undergo prenatal genetic screening.

Newborn screening

This type of test is done to diagnose any sort of genetic abnormalities such as hypothyroidism, sickle cell, or any other metabolic disorder in a newborn. The timely diagnostic will help in starting the treatment at the earliest.

Preimplantation testing

This type of testing is only recommended when partners are planning to undergo IVF (In Vitro Fertilization) for conceiving a baby. In this type of testing, embryos are being examined for any genetic abnormalities before planting them in the uterus. If the report comes out satisfactorily, then only the process of implantation is carried out for a safer and healthy pregnancy.

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More Information

Genetic testing

There are hardly any risks of genetic testing as it only requires a blood test of a mother without harming the fetus. On the other hand, there are minimal chances of a miscarriage if one goes for prenatal testing such as chorionic villus or amniocenteses.
So, it is advisable to consult your physician or gynecologist before undergoing prenatal genetic testing as it involves emotional, social, and financial risks, too. There are various arguments against genetic testing, too, so it is always better to get aware of all the factors involved concerning genetic testing.
Before undergoing genetic testing, you must gather as much information about your family’s medical history. Share this information with your gynecologist or genetic counselor to understand these issues and also understand the after-effects of genetic testing.
If you are aware of any genetic disease running in your family then you must inform them before undergoing the test. Maybe their opinion can be of great help to you. Having a detailed discussion regarding this with your family member may also give you a sense of feel as to how they will respond post-test.
Also, you must talk with your insurance advisor about genetic testing as most insurance policies don’t pay for this test.
Therefore, it is very much necessary to understand the genetic testing pros and cons before booking an appointment for the same.
Based on the test recommended by your doctor, collection of the prescribed sample is done (it can be blood, skin, amniotic fluid, or any other tissue) and sent to the lab for diagnostic purposes
  • Blood sample
    The blood sample is taken by inserting a needle into the vein of your arm. Initially, a blood test is only recommended for genetic testing in pregnancy’s first trimester. For a newborn's screening, the sample is taken by pricking the heel of the baby.
    If you are looking for a reliable diagnostic center concerning newborn screening tests UAE, contact Uturn9.
  • Cheek swab
    In certain cases, a sample is taken from the inside of the cheek with the help of a swab for genetic testing.
  • Amniocentesis
    Here, your amniotic fluid is being considered for genetic testing. In this process, the doctor inserts a hollow, thin needle into your uterus through your abdominal wall and collects the amniotic fluid
  • Chorionic villus sampling
    A tissue sample from the placenta is taken for this type of genetic testing. In this type of test either the sample is collected with the help of a tube through the cervix or by using a thin needle through the abdominal wall into the uterus. It depends upon the condition of the patient.
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Results

The amount of time it takes for you to receive your genetic test results depends on the type of test and your health care facility. Talk to your doctor, medical geneticist or genetic counselor before the test about when you can expect the results and have a discussion about them.

Genetic counseling

Genetic counselling supports patients with personalized approaches to help them better understand the cause, and the implications of various genetic conditions.
The counsellor helps facilitate informed decision-making regarding testing options, test results, prevention and life planning
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